Voltaren retard 100mg 10 tablet fiyat

Clinical trial and epidemiological data suggest that use of diclofenac, particularly at high dose mg daily and in long term treatment may be associated with a small increased risk of arterial thrombotic events for example myocardial infarction or stroke. Patients with significant risk factors for cardiovascular events e.

As the cardiovascular effects of diclofenac may increase with dose and duration of exposure, the shortest duration possible and the lowest effective daily dose should be used. The patient's need for symptomatic relief and response to therapy should be re-evaluated periodically. Gastrointestinal bleeding, ulceration and perforation GI bleeding, ulceration or perforation, which can be fatal, has been reported with all NSAIDs at any time during treatment, with or without warning symptoms or a previous history of serious GI events.

The risk of GI bleeding, ulceration or perforation is higher with increasing NSAID doses, in patients with a history of ulcer, particularly if complicated with haemorrhage or perforation see section 4.

These patients should commence treatment on the lowest dose available. Combination therapy with protective agents e. Patients with a history of GI toxicity, particularly when elderly, should report any unusual abdominal symptoms especially GI bleeding particularly in the initial stages of treatment.

Caution should be advised in patients receiving concomitant medications which could increase the risk of ulceration or bleeding, such as oral corticosteroids, anticoagulants such as warfarin, selective serotonin-reuptake inhibitors or anti-platelet agents such as aspirin see section 4.

When GI bleeding or ulceration occurs in patients receiving diclofenac, the treatment should be withdrawn. NSAIDs should be given with care in patients with a history of gastrointestinal disease ulcerative colitis, Crohn's disease, haematemesis, melaena, haematological abnormalities, or bleeding diathesis as these conditions may be exacerbated see section 4. SLE and mixed connective tissue disease In patients with systemic lupus erythematosus SLE and mixed connective tissue disorders there may be an increased risk of aseptic meningitis see section 4.

Dermatological Serious skin reactions, some of them fatal, including exfoliative dermatitis, Stevens-Johnson syndrome, and toxic epidermal necrolysis, have been reported very rarely in association with the use of NSAIDs see section 4. Patients appear to be at highest risk for these early in the course of therapy: Impaired female fertility The use of Volsaid may impair female fertility and is not recommended in women attempting to conceive.

In women who have difficulties conceiving or who are undergoing investigation of infertility, withdrawal of Volsaid should be considered. Other analgesics including cyclooxygenase-2 selective inhibitors Avoid concomitant use of two or more NSAIDs including aspirin as this may increase the risk of adverse effects see section 4. Anti-hypertensives Reduced anti-hypertensive effect. Diuretics Reduced diuretic effect. Increased serum potassium levels may result when diclofenac is given concomitantly with potassium-sparing diuretics.

Serum potassium levels should therefore be monitored. Lithium Decreased elimination of lithium. Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.

Taking Voltaren with food and drink Voltaren gastro-resistant tablets should be swallowed whole with a glass of water or other liquid. It is recommended Voltaren tablets are to be taken before meals or on an empty stomach. Elderly Elderly patients may be more sensitive to the effects of Voltaren than other adults. Therefore they should especially carefully follow the doctor's instructions and adopt minimum number of gastro-resistant tablets, relieving symptoms.

It is very important for older patients to promptly report to their physician any side effects. Children and adolescents Due to its unit dose Voltaren gastro-resistant tablets 50 mg should not be prescribed to children and adolescents under 14 years. Voltaren tablets a 25 mg can be used in patients less than 14 years. Voltaren gastro-resistant tablets should not be given to children under 12 months.

Pregnancy and lactation If you are pregnant or think you may be pregnant, contact your doctor. You should not take Voltaren gastro-resistant tablets if you are pregnant unless absolutely necessary. As with other anti-inflammatory drugs should not take Voltaren gastro-resistant tablets in the last 3 months of pregnancy because it may harm your unborn baby or cause problems at birth.

You should tell your doctor if you are breastfeeding. You should not breastfeed while taking Voltaren, as this could harm your child. Consult your doctor or pharmacist before taking any medicine. Your doctor will discuss with you the potential risk of taking Voltaren during pregnancy or lactation. Women of childbearing potential Voltaren can complicate pregnancy. You should not take Voltaren gastro-resistant tablets, plan to become pregnant or have difficulty conceiving. Driving and using machines Voltaren is unlikely to affect the ability to drive, operate machinery or other activities requiring alertness.

Important information about some of the ingredients of Voltaren gastro-resistant tablets Voltaren gastro-resistant tablets 25 and 50mg contain lactose. Clinical trial and epidemiological data suggest that the use of diclofenac, particularly at high doses mg daily and in long term treatment may be associated with a small increased risk of arterial thrombotic events for example myocardial infarction or stroke.

Patients with congestive heart failure NYHA-1 and patients with significant risk factors for cardiovascular events e. As the cardiovascular risks of diclofenac may increase with dose and duration of exposure, the shortest duration possible and the lowest effective daily dose should be used.

The patient's need for symptomatic relief and response to therapy should be re-evaluated periodically. Patients should remain alert for the signs and symptoms of serious arteriothrombotic events e.

Patients should be instructed to see a physician immediately in case of such an event. Patients with defects of haemostasis should be carefully monitored. Pre-existing asthma In patients with asthma, seasonal allergic rhinitis, swelling of the nasal mucosa i. Therefore, special precaution is recommended in such patients readiness for emergency. This is applicable as well for patients who are allergic to other substances, e. All patients who are receiving non-steroidal anti-inflammatory agents should be monitored as a precautionary measure e.

This is particularly important in the elderly. Caution is recommended when co-prescribing diclofenac with potent CYP2C9 inhibitors such as voriconazole , which could result in a significant increase in peak plasma concentrations and exposure to diclofenac due to inhibition of diclofenac metabolism. If used concomitantly, diclofenac may raise plasma concentrations of lithium. Monitoring of the serum lithium level is recommended.

If used concomitantly, diclofenac may raise plasma concentrations of digoxin. If gastro-intestinal bleeding or ulceration occurs in patients receiving Voltarol the drug should be withdrawn.

As with all NSAIDs, including diclofenac, close medical surveillance is imperative and particular caution should be exercised when prescribing diclofenac in patients with symptoms indicative of gastrointestinal GI disorders or with a history suggestive of gastric or intestinal ulceration, bleeding or perforation see section 4. The risk of GI bleeding, ulceration or perforation is higher with increasing NSAID doses in patients with a history of ulcer, particularly if complicated with haemorrhage or perforation see section 4.

To reduce the risk of GI toxicity in patients with a history of ulcer, particularly if complicated with haemorrhage or perforation and in the elderly, the treatment should be initiated and maintained at the lowest effective dose.

Combination therapy with protective agents e. Patients with a history of GI toxicity, particularly the elderly, should report any unusual abdominal symptoms especially GI bleeding particularly in the initial stages of treatment.

Caution is recommended in patients receiving concomitant medications which could increase the risk of ulceration or bleeding, such as oral corticosteroids, anticoagulants such as warfarin, anti-platelet agents such as aspirin or selective serotonin-reuptake inhibitors see section 4. Close medical surveillance and caution should be exercised in patients ulcerative colitis or Crohn's disease, as their condition may be exacerbated see section 4.

Hepatic effects Close medical surveillance is required when prescribing Voltarol to patients with impaired hepatic function, as their condition may be exacerbated. During prolonged treatment with Voltarol, regular monitoring of hepatic function is indicated as a precautionary measure. If abnormal liver function tests persist or worsen, if clinical signs or symptoms consistent with liver disease develop, or if other manifestations occur e.

Hepatitis may occur with use of diclofenac without prodromal symptoms. Caution is called for when using Voltarol in patients with hepatic porphyria, since it may trigger an attack. Renal effects As fluid retention and oedema have been reported in association with NSAID therapy, including diclofenac, particular caution is called for in patients with impaired cardiac or renal function, history of hypertension, the elderly, patients receiving concomitant treatment with diuretics or medicinal products that can significantly impact renal function and in those patients with substantial extracellular volume depletion from any cause, e.

Monitoring of renal function is recommended as a precautionary measure when using Voltarol in such cases. Discontinuation of therapy is usually followed by recovery to the pre-treatment state.

Tags: buy terramycin for dogs buy zyloprim drug tegretol cr 400mg para que serve depakote er online price wellbutrin 300mg extended release buy rohypnol online