Also, bone pain and softening of the bone which may lead to fractures may occur as a consequence of kidney problems. If you have had bone problems in the past, your healthcare provider may want to do tests to check your bones or may prescribe medicines to help your bones. Tell your healthcare provider right away if any of these side effects continue or if they bother you.
Rash may be serious in a small number of patients. Rash may be a serious problem in some children. If a rash develops, call your healthcare provider right away. Other common side effects include: Other possible side effects: Changes in body fat have been seen in some people taking anti-HIV-1 medicines. Increase of fat in the upper back and neck, breasts, and around the trunk may happen. Loss of fat from the legs, arms, and face may also happen.
The cause and long-term health effects of these changes in body fat are not known. Skin discoloration small spots or freckles may also happen. If you notice any symptoms of infection, contact your healthcare provider right away. The recommended dose of Efavirenz Teva for adults is mg once a day. Efavirenz Teva tablets are not suitable for children weighing less than 40 kg.
Efavirenz-containing capsules are available for these patients. The dose of Efavirenz Teva needs to be reduced in patients taking voriconazole used to treat fungal infections. Patients taking rifampicin an antibiotic may need to take a higher dose of Efavirenz Teva. For full details, see the summary of product characteristics also part of the EPAR. How does Efavirenz Teva work?
It blocks the activity of reverse transcriptase, an enzyme produced by HIV that allows it to infect cells in the body and make more viruses.
By blocking this enzyme, Efavirenz Teva, taken in combination with other antiviral medicines, reduces the amount of HIV in the blood and keeps it at a low level. How has Efavirenz Teva been studied? Because Efavirenz Teva is a generic medicine, studies in patients have been limited to tests to determine that it is bioequivalent to the reference medicine, Sustiva.
Two medicines are bioequivalent when they produce the same levels of the active substance in the body. What are the benefits and risks of Efavirenz Teva? It is recommended that estimated CrCl be assessed in all patients prior to initiating therapy and as clinically appropriate.
Estimated CrCl, serum phosphorus, urine glucose, and urine protein should be assessed for patients at risk of renal dysfunction prior to initiation and periodically during therapy, including patients who have previously experienced renal events while receiving adefovir dipivoxil. Cases of acute renal failure after initiation of high-dose or multiple NSAIDs, some requiring hospitalization and renal replacement therapy, have been reported in HIV-infected patients with risk factors for renal dysfunction who appeared stable on tenofovir DF; consider alternatives to NSAIDs in these patients.
Barrier contraception must always be used in combination with other methods of contraception e. Because of the long half-life of efavirenz, adequate contraceptive measures are recommended for 12 weeks after discontinuation of ATRIPLA. Efavirenz, emtricitabine, and tenofovir have been detected in human milk. Mothers should be instructed not to breastfeed because the risks of exposure to these products to the infant are unknown, and because of the potential risks of HIV-1 transmission.
Mild-to-moderate rash is a common side effect of efavirenz. ATRIPLA should be discontinued in patients developing severe rash associated with blistering, desquamation, mucosal involvement, or fever. For patients who have had a life-threatening cutaneous reaction e. Liver enzymes should be monitored before and during treatment in patients with underlying hepatic disease, including hepatitis B or C infection; in patients with marked transaminase elevations; and when ATRIPLA is administered with ritonavir or other medications associated with liver toxicity.
A few of the postmarketing reports of hepatic failure, including cases in patients with no pre-existing hepatic disease or other identifiable risk factors, were characterized by a fulminant course, progressing in some cases to transplantation or death.
Liver enzyme monitoring should be considered for patients without pre-existing hepatic dysfunction or other risk factors.
Have ever had seizures or are taking medicine for seizures. There have been occasional reports of suicide, delusions, psychosis-like behavior, and catatonia, but it could not be determined if efavirenz was efavirenz cause. Most of these serious side effects occurred in patients with a chronic liver disease such as hepatitis infection, but there have also been a few reports in patients without any existing liver disease. For full details, see the summary of product characteristics also part of the EPAR. If you have had bone problems in the past, your healthcare provider may want to do tests to check your bones or may prescribe medicines to teva your bones. Increase of fat in the upper back and neck, breasts, efavirenz teva precio, and around the trunk may happen. By blocking this enzyme, Efavirenz Teva, precio in combination with other antiviral medicines, reduces the amount of Online norco prescription in the blood and keeps it at a low level. Too much lactic acid in your blood lactic acidosis. This is a serious but rare medical emergency. In rare cases, severe liver problems can happen that can lead to death. What is Efavirenz Teva?
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