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Hepatotoxicity Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Reserve concomitant prescribing of hydrocodone bitartrate and acetaminophen tablets and benzodiazepines or other CNS depressants for use in patients for whom alternative treatment options are inadequate. Limit dosages and durations to the minimum required.

Follow patients for signs and symptoms of respiratory depression and sedation. The risk of addiction can occur in appropriately prescribed patients and at recommended dosages with misuse or abuse. Life-Threatening Respiratory Depression Serious, life-threatening, or fatal respiratory depression has been reported with the use of opioids, even if used as recommended. The risk is greatest during initiation of therapy or following a dose increase. Monitor for respiratory depression, especially during the first hours.

Observe newborns for signs of neonatal opioid withdrawal syndrome and manage accordingly. Frequently monitor and adjust dose as needed.

Monitor and advise both patients and caregivers of the risks including use with alcohol and illicit drugs. Inform patients not to drive or operate heavy machinery until the effects are known. Elderly, Cachectic, or Debilitated Patients Significant chronic obstructive pulmonary disease or cor pulmonale; substantial decreased respiratory reserve, hypoxia, hypercapnia; or pre-existing respiratory depression increases the risk of decreased respiratory drive, even at recommended dosages.

Elderly, cachectic, or debilitated patients are at greater risk for life-threatening respiratory depression than younger, healthier patients. These actions are justified by imagining fewer deaths will happen to irresponsible morons. There is no proof for this ever offered. This is who is telling people like me that we cannot control ourselves. The facts are we can and do. If you read some of the posts here from folks who have serious addictions you might be more sympathetic to that aspect of it.

The problem is that folks like yourself, who need these medications, face more difficulties because of the abuse of others. This happens in all aspects of life, where honest folks have to deal with more crap ever fly on a plane anymore? But just like we now have to put up with the TSA and luggage searches to ensure our protection, so do you need to understand the increased difficulties you will have to put up with so that others may be protected.

Will this cause permanent liver damage. I am concern however about the long term health affects which includes liver and breathing problems. I am in perfect health, but again I am concerned specially when I read other articles about addiction and overdosing on this stuff.

To recap my question is: Will taking one Hydrocodon-Acetaminoph 7. My doctor who has prescribed me this meds and who is is a very good doctor understands my concerns and believes I have nothing to worry about since the prescription is being tightly controlled..

Thank your for your time… David 8: This tree grows in Indonesia and has worked for many. Whether it is pain or drug addiction please do yourself a favor and research this. I have Spinastinosis and RA. I have titanium in my back already and a new hip. Tolerance to hydrocodone was through the roof. I came across one of many videos on YouTube. Please research this leaf which is in the coffee family. It has many uses and is very versatile.

Good luck and Godspeed to you. I am so scared Lydia Addiction Blog Call the Poison Control Center at for an assessment of overdose risk. I take little pieces of Narco. I take them for D. Im afraid to take a whole pill because im a panicky person. But im wondering if i do this long term, it will eventually kick my butt. Even if its small doses.

Not like im going to take the whole pill at once, but i still worry. Ive been doing this for about 4 months now. I could easily stop but it helps ease pain for a while. What scares me is the crisis going on right now.

Dont buy them off the street. They could have a opioid named fenteyal in them. Wow Lisa the worry wart. I am currently on meds for high aniexy mike 9: I am looking for christian counseling information Can I get advise? Usually on Wednesday, Friday and Saturday when I got out socially. Have for about 2 years now. Trying to get off the meds. Nothing else helps for the nerve pain.

Any suggestions Susan 1: Have had severe burning in my back since my first surgery in This dose just takes the edge off so I can just function. I do not take more than my doctor prescribes. Going to Johns Hopkins to see what else can be done.

I started at just one a day. I also take gabapetnin pprn and ambien mg. And I try to only take the Vicodin when I cant handle the pain. Lately -last month or so- I find that in the morning I wake up feeling like death. Hot cold sweats, freezing cold. No energy T all. And I will take a Vicodin and within 30 min I have stopped shivering and feel so much better. Am I getting addicted?

Should I be worried about over dose on acetaminophen? Is this a normal side effect or could i be allergic to the medication? A single or multiple overdose with hydrocodone and acetaminophen is a potentially lethal polydrug overdose, and consultation with a regional poison control center is recommended.

Immediate treatment includes support of cardiorespiratory function and measures to reduce drug absorption. Vomiting should be induced mechanically, or with syrup of ipecac , if the patient is alert adequate pharyngeal and laryngeal reflexes. The first dose should be accompanied by an appropriate cathartic. If repeated doses are used, the cathartic might be included with alternate doses as required.

Hypotension is usually hypovolemic and should respond to fluids. Vasopressors and other supportive measures should be employed as indicated. A cuffed endo-tracheal tube should be inserted before gastric lavage of the unconscious patient and, when necessary, to provide assisted respiration.

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