In animal studies, a week oral toxicity study in mice and week and week oral toxicity studies in rats and cynomolgus monkeys have shown the kidney to be the major target organ of mesalamine toxicity. Patients with preexisting renal disease, increased BUN or serum creatinine, or proteinuria should be carefully monitored, especially during the initial phase of treatment. Mesalamine-induced nephrotoxicity should be suspected in patients developing renal dysfunction during treatment.
Do not drive or perform other possibly unsafe tasks until you know how you react to it. Mesacol suppository may stain clothing, other fabrics, or surfaces. Avoid contact with your clothes, other fabrics, or surfaces. Salicylates have been linked to a serious illness called Reye syndrome. Do not give this medicine to a child, or teenager, or a person who has the flu, chickenpox, or a viral infection. Contact your doctor with any questions or concerns. Lab tests, including kidney function, liver function, or complete blood cell counts, may be performed while you use this medicine.
These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments. Use this medicine with caution in the elderly; they may be more sensitive to its effects, especially blood problems.
It should be used with extreme caution in children; safety and effectiveness in children have not been confirmed. I too was told by my doctor to lower the dosage to 2 pills a day recently, but found when I did that I started getting bloody stools again. So I went back to 4 a day. I had a blood test recently and found my testosterone levels have lowered since taking this, not a pleasing side effect. I started on four tablets a day, at one stage increased to six, but for the last two years have given myself a "maintenance" level of two a day because my UC is more or less in remission.
My specialist advised I could give it away altogether, but when I tried this, I had a flare-up. Please note that the product appearance may vary from actual product received depending on availability. Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price.
Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in: The medicine label will tell you how often to give it to your child. Ideally, these times are about 12 hours apart, for example some time between 7 and 8 am, and between 7 and 8 pm. Three times a day: Ideally, these times are at least 4 hours apart. How much should I give?
Your doctor will work out the amount of mesalazine the dose that is right for your child. The dose will be shown on the medicine label. How should I give it? Suppositories are administered through the anus into the rectum. They must not be taken by mouth. Ideally your child should open their bowels do a poo before you administer mesalazine suppositories. Wash your hands thoroughly with soap and hot water before and after inserting the suppositories.
If your child empties their bowels does a poo within 15 minutes of inserting a suppository, you will need to insert a new one. Suppositories - See How to give rectal medicines for more information Your child should be lying on their left side or front. Unwrap the suppository and hold it with the rounded end close to the back passage. Talk to your doctor or pharmacist about whether taking a supplement is recommended or if you have any questions or concerns.
Pentasa may deplete vitamin B12 How can this nutrient deficiency impact me? Vitamin B12, also known as cyancobalamin or cobalamin, is involved in the body's metabolism, DNA synthesis, and red blood cells. It also helps maintain the nervous system.
Vitamin B12 deficiency is most common in people on meatless diets since it is not found in grains, fruits, or vegetables. Pentasa may deplete iron How can this nutrient deficiency impact me? Iron is a nutrient that is vital to the function of red blood cells in transporting oxygen throughout the body. It also plays a role in the body's immune system, metabolism, and energy production.
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