To minimize dizziness and lightheadedness , get up slowly when rising from a sitting or lying position. Older adults may be more sensitive to the side effects of this drug, especially QT prolongation see above.

This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Consult your doctor before breast -feeding. What should I know regarding pregnancy, nursing and administering Ondansetron Hcl to children or the elderly?

Interactions Your healthcare professionals e. Do not start, stop or change the dosage of any medicine before checking with them first. This drug should not be used with the following medication because a very serious interaction may occur: If you are currently using the medication listed above, tell your doctor or pharmacist before starting ondansetron.

Before using this medication, tell your doctor of all nonprescription and prescription medication you may use, especially of: Ask your doctor or pharmacist for more details. Many drugs besides ondansetron may affect the heart rhythm QT prolongation , including dofetilide , pimozide , procainamide , amiodarone , quinidine , sotalol , macrolide antibiotics such as erythromycin , among others.

Therefore, before using ondansetron, report all medications you are currently using to your doctor or pharmacist. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. It is not known whether ondansetron passes into breast milk or if it could harm a nursing baby.

Tell your doctor if you are breast-feeding a baby. Ondansetron is not approved for use by anyone younger than 4 years old. Ondansetron orally disintegrating tablets may contain phenylalanine. How should I take ondansetron? Take ondansetron exactly as prescribed by your doctor. Follow all directions on your prescription label.

Do not take this medicine in larger or smaller amounts or for longer than recommended. Ondansetron can be taken with or without food. The first dose is usually taken before the start of your surgery, chemotherapy, or radiation treatment. Follow your doctor's dosing instructions very carefully. Take the ondansetron regular tablet with a full glass of water.

What should I know regarding pregnancy, nursing and administering Zofran ODT to children or the elderly? Interactions Your healthcare professionals e. Do not start, stop or change the dosage of any medicine before checking with them first. This drug should not be used with the following medication because a very serious interaction may occur: If you are currently using the medication listed above, tell your doctor or pharmacist before starting ondansetron.

Before using this medication, tell your doctor of all nonprescription and prescription medication you may use, especially of: Ask your doctor or pharmacist for more details. Many drugs besides ondansetron may affect the heart rhythm QT prolongation , including dofetilide , pimozide , procainamide , amiodarone , quinidine , sotalol , macrolide antibiotics such as erythromycin , among others. Therefore, before using ondansetron, report all medications you are currently using to your doctor or pharmacist.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use.

Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Does Zofran ODT interact with other medications? Overdose If someone has overdosed and has serious symptoms such as passing out or trouble breathing , call Otherwise, call a poison control center right away.

US residents can call their local poison control center at Canada residents can call a provincial poison control center. Notes Do not share this product with others. Consult your doctor for more details. In patients treated with potent inducers of CYP3A4 i. However, on the basis of available data, no dosage adjustment for ondansetron is recommended for patients on these drugs [see Clinical Pharmacology Tramadol Although no pharmacokinetic drug interaction between ondansetron and tramadol has been observed, data from 2 small trials indicate that when used together, ondansetron may increase patient-controlled administration of tramadol.

Monitor patients to ensure adequate pain control when ondansetron is administered with tramadol. Chemotherapy Carmustine, etoposide, and cisplatin do not affect the pharmacokinetics of ondansetron. In a crossover trial in 76 pediatric patients, intravenous ondansetron did not increase systemic concentrations of high-dose methotrexate.

Alfentanil and Atracurium Ondansetron does not alter the respiratory depressant effects produced by alfentanil or the degree of neuromuscular blockade produced by atracurium. Interactions with general or local anesthetics have not been studied.

Published epidemiological studies on the association between ondansetron and fetal outcomes have reported inconsistent findings and have important methodological limitations hindering interpretation [see Data].

The background risk of major birth defects and miscarriage for the indicated population is unknown. Data Human Data Methodological limitations of the epidemiology studies preclude a reliable evaluation of the potential risk of adverse fetal outcomes with the use of ondansetron in pregnancy.

Two large retrospective cohort studies of ondansetron use in pregnancy have been published. In one study with 1, infants born to women who reported the use of ondansetron or received an ondansetron prescription in the first trimester, no increased risk for major congenital malformations was seen in aggregate analysis. In this same study, however, a sub-analysis for specific malformations reported an association between ondansetron exposure and cardiovascular defect odds ratio OR 1.

The second study examined 1, women who received ondansetron prescription during pregnancy and reported no association between ondansetron exposure and major congenital malformations, miscarriage or stillbirth, and infants of low birth weight or small for gestational age. Important methodological limitations with these studies include the uncertainty of whether women who filled a prescription actually took the medication, the concomitant use of other medications or treatments, and other unadjusted confounders that may account for the study findings.

However, this association could be a chance finding, given the large number of drugs-birth defect comparisons in this study.

It is unknown whether ondansetron exposure in utero in the cases of cleft palate occurred during the time of palate formation the palate is formed between the 6th and 9th weeks of pregnancy or whether mothers of infants with cleft palate used other medications or had other risk factors for cleft palate in the offspring.

In addition, no cases of isolated cleft palate were identified in the aforementioned two large retrospective cohort studies. Who should NOT take this medication? Do not take this medication if you: Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication.

If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor. Many of these side effects can be managed, and some may go away on their own over time. Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects. Check with your doctor as soon as possible if any of the following side effects occur: Check with your doctor if you notice any symptom that worries you while you are taking this medication.

Are there any other precautions or warnings for this medication? Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

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Ask your doctor san pharmacist for more details. Discuss the risks and benefits with your doctor. This product may contain inactive ingredients, which can cause allergic reactions 8mg other problems. Do not stop taking this medication without consulting your doctor. Tell your doctor if you are pregnant. Older adults may be more sensitive to the 8mg effects of this drug, especially QT prolongation see above. If you miss a dose, take it as soon as you remember unless it is near the time for the next dose. To prevent nausea after surgery, take ondansetron 1 hour before the start of ondansetron. To help you remember, take it at the same times each day. Do not push the tablet through the foil. If you notice odt symptoms of NMS such as high fever, muscle stiffness, san or loss of consciousness, sweating, ondansetron or irregular tab, or fainting, get immediate medical attention. Store at room temperature odt from moisture, heat, and tab. If you notice other effects not listed above, contact your doctor or pharmacist.

What Is Ondansetron Orally Disintegrating Tablet Used For?

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