Cefaclor Sandoz is not addictive. Some of the symptoms of an allergic reaction may include wheezing, shortness of breath, swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing, skin rash, itching or hives. You may be more likely to have an allergic reaction to Cefaclor Sandoz if you are allergic to penicillin medicines. Do not give Cefaclor Sandoz to a premature baby or to a baby less than one month old.
The safety and effectiveness of Cefaclor Sandoz have not been established in this age group. Do not use Cefaclor Sandoz if the packaging is torn or shows signs of tampering or if the medicine does not look quite right. Do not use Cefaclor Sandoz after the expiry date printed on the pack has passed. If you are not sure whether you should start taking Cefaclor Sandoz, contact your doctor. Before you start to take it Tell your doctor if: You may have an increased chance of being allergic to Cefaclor Sandoz if you are allergic to penicillins.
Cefaclor Sandoz may affect your developing baby if you take it during pregnancy. Your doctor will discuss the risks and benefits of using Cefaclor Sandoz during pregnancy. Cefaclor Sandoz passes into breast milk and may affect your baby. Your doctor will discuss the risks and benefits of using Cefaclor Sandoz when breast-feeding.
Taking other medicines Tell your doctor or pharmacist if you are taking any other medicines, including any medicines that you buy without a prescription from your pharmacy, supermarket or health food shop.
Some medicines may interfere with Cefaclor Sandoz. You may need to take different amounts of your medicine, or you may need to take different medicines. Your doctor will advise you. Talk to your doctor about the need for an additional method of contraception while taking Cefaclor Sandoz. Some antibiotics may decrease the effectiveness of some birth control pills. Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking Cefaclor Sandoz.
How to take Cefaclor Sandoz Follow all directions given to you by your doctor or pharmacist carefully.
These directions may differ from the information contained in this leaflet. If you do not understand the instructions on the container, ask your doctor or pharmacist for help.
How much to take Your doctor will tell you how much Cefaclor Sandoz you need to take. This will depend on the type of infection you have. Adults The usual dose of Cefaclor Sandoz is mg every 8 to 12 hours. This dose may vary depending on your condition. Children The dose for children varies according to the age of the child, their weight and the type of infection. Your doctor and pharmacist will tell you the right amount to give your child. How to take it Always shake the bottle before measuring the correct volume to be taken using a metric medicine measure.
Go to top of the page 4. The most frequent side-effect has been diarrhoea. It is rarely severe enough to warrant cessation of therapy. Colitis, including rare instances of pseudomembranous colitis, has been reported. Nausea and vomiting have also occurred. Allergic reactions, such as morbilliform eruptions, pruritus and urticaria, have been observed. These reactions usually subside upon discontinuation of therapy. Lymphadenopathy and proteinuria are infrequent; there are no circulating immune complexes and no evidence of sequelae.
No serious sequelae have been reported. More severe hypersensitivity reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, and anaphylaxis have been reported rarely. Anaphylactoid events may be manifested by solitary symptoms, including angioedema, asthenia, edema including face and limbs , dyspnea, paresthesias, syncope, hypotension, or vasodilatation.
Anaphylaxis may be more common in patients with a history of penicillin allergy. Rarely, hypersensitivity symptoms may persist for several months. Gastrointestinal symptoms occur in about 2. Nausea and vomiting have been reported rarely. As with some penicillins and some other cephalosporins, transient hepatitis and cholestatic jaundice have been reported rarely. Other effects considered related to therapy included eosinophilia 1 in 50 patients , genital pruritus, moniliasis or vaginitis about 1 in 50 patients , and, rarely, thrombocytopenia or reversible interstitial nephritis.
Causal Relationship Uncertain CNS Rarely, reversible hyperactivity, agitation, nervousness, insomnia, confusion, hypertonia, dizziness, hallucinations, and somnolence have been reported. Transitory abnormalities in clinical laboratory test results have been reported. Although they were of uncertain etiology, they are listed below to serve as alerting information for the physician. Renal Slight elevations in BUN or serum creatinine less than 1 in or abnormal urinalysis less than 1 in Cephalosporin-class Adverse Reactions In addition to the adverse reactions listed above that have been observed in patients treated with cefaclor, the following adverse reactions and altered laboratory tests have been reported for cephalosporin-class antibiotics: Several cephalosporins have been implicated in triggering seizures, particularly in patients with renal impairment when the dosage was not reduced.
If seizures associated with drug therapy occur, the drug should be discontinued. The severity of the epigastric distress and the diarrhea are dose-related.
If other symptoms are present, it is probable that they are secondary to an underlying disease state, an allergic reaction, or the effects of other intoxication. Treatment To obtain up-to-date information about the treatment of overdose, a good resource is your certified Regional Poison Control Center. In managing overdosage, consider the possibility of multiple drug overdoses, interaction among drugs, and unusual drug kinetics in your patient.
Unless 5 times the normal dose of cefaclor has been ingested, gastrointestinal decontamination will not be necessary. Protect the patient's airway and support ventilation and perfusion. Meticulously monitor and maintain, within acceptable limits, the patient's vital signs, blood gases, serum electrolytes, etc. Absorption of drugs from the gastrointestinal tract may be decreased by giving activated charcoal, which, in many cases, is more effective than emesis or lavage; consider charcoal instead of or in addition to gastric emptying.
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