The mg tablet of Augmentin and the mg chewable tablet should NOT be substituted for each other, as they are not interchangeable and the mg tablet should not be used in children weighing less than 40 kg.
The mg tablet of Augmentin and the mg chewable tablet do not contain the same amount of clavulanic acid. The mg tablet of Augmentin contains mg of clavulanic acid whereas the mg chewable tablet contains Since both the mg and mg tablets of Augmentin contain the same amount of clavulanic acid mg, as the potassium salt , two mg tablets of Augmentin are not equivalent to one mg tablet of Augmentin.
Contraindications Serious Hypersensitivity Reactions Augmentin is contraindicated in patients with a history of serious hypersensitivity reactions e. Warnings and Precautions Hypersensitivity Reactions Serious and occasionally fatal hypersensitivity anaphylactic reactions have been reported in patients receiving beta-lactam antibacterials, including Augmentin. Before initiating therapy with Augmentin, careful inquiry should be made regarding previous hypersensitivity reactions to penicillins, cephalosporins, or other allergens.
If an allergic reaction occurs, Augmentin should be discontinued and appropriate therapy instituted. Hepatic Dysfunction Hepatic dysfunction, including hepatitis and cholestatic jaundice has been associated with the use of Augmentin.
Hepatic toxicity is usually reversible; however, deaths have been reported. Hepatic function should be monitored at regular intervals in patients with hepatic impairment.
Clostridium difficile Associated Diarrhea CDAD Clostridium difficile associated diarrhea CDAD has been reported with use of nearly all antibacterial agents, including Augmentin, and may range in severity from mild diarrhea to fatal colitis.
Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. Hypertoxin-producing strains of C.
CDAD must be considered in all patients who present with diarrhea following antibacterial use. Careful medical history is necessary since CDAD has been reported to occur over 2 months after the administration of antibacterial agents.
Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C. Skin Rash in Patients with Mononucleosis A high percentage of patients with mononucleosis who receive amoxicillin develop an erythematous skin rash.
Thus, Augmentin should not be administered to patients with mononucleosis. Potential for Microbial Overgrowth The possibility of superinfections with fungal or bacterial pathogens should be considered during therapy. Phenylketonurics Augmentin Chewable tablets and Augmentin Powder for Oral Solution contain aspartame which contains phenylalanine.
Each mg chewable tablet of Augmentin contains 2. The other formulations of Augmentin do not contain phenylalanine. Adverse Reactions The following are discussed in more detail in other sections of the labeling: Anaphylactic reactions [see Warnings and Precautions 5. If overdose is suspected, contact your local poison control center or emergency room immediately.
US residents can call the US national poison hotline at Canadian residents should call their local poison control center directly. Symptoms of overdose may include: Do not share this medication with others. This medication has been prescribed for your current condition only.
Do not use it later for another infection. A different medication may be necessary in those cases. Consult your doctor for more details. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up. Store at or below room temperature 77 degrees F or 25 degrees C away from light and moisture.
Do not store in the bathroom. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. If overdose is suspected, contact your local poison control center or emergency room immediately.
US residents can call the US national poison hotline at Canadian residents should call their local poison control center directly. Symptoms of overdose may include: Do not share this medication with others.
This medication has been prescribed for your current condition only. Do not use it later for another infection unless told to do so by your doctor. A different medication may be necessary in those cases. Consult the doctor for more details. If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
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